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Price $5.99
10 pills per strip
Wt. 75gm
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Enapril(5mg)
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What is
Enapril(5mg)
?
Enalapril is de-esterified into the active enalaprilat resulting in potent inhibition of ACE thus leading to reduced levels of angiotensin II and aldosterone. Clinically, BP is reduced, salt and water retention is corrected. Ventricular hypertrophy is reversed. Renal blood flow is increased but in patients with renal impairment there may be oliguria or acute renal failure.
Storage
Intravenous: Store below 30°C. Oral: Store below 30°C.
Dosage
Adult: Initially, 5 mg at bedtime. Maintenance: 10-20 mg once daily increased up to 40 mg in divided doses in severe hypertension. Max: 40 mg/day.
Child: 80 mcg/kg once daily. Max: 5 mg/day.
Elderly: May initiate at lower doses at 2.5 mg daily.
Renal impairment: Initial dose should be halved.
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Side Effects
Initial hypotension may be severe and prolonged. Dizziness, headache, fatigue, persistent dry cough, abnormal taste, lassitude, rash, neutropenia, renal impairment or failure.
Potentially Fatal: Angioedema.
Precautions
Impaired renal function. Hyperkalaemia, hypovolaemia, collagen vascular disease, valvular stenosis, during or immediately before or after anaesthesia, unilateral renal artery stenosis. Hypotension due to volume depletion, diuretic therapy. Monitor WBC count. Lactation, children.
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